Anti-IGF-IR Antibody, β-subunit, clone 1-2
IGF-IR depletion in stably transfected cells was confirmed by immunoblot analysis Fig 4A top left panel Induction of the cytoplasmic β 1 variant was confirmed by FACS Fig 4A lower panels Upon induction, IGF-IR would be expected to redistribute and bind to both the endogenous β 1 and exogenous cytoplasmic
IGF-IR overexpression during embryonic or pubertal phases resulted in increased tumor multiplicity compared to adult and primiparous mice Table 1 The average number of mammary tumors in mice where IGF-IR expression was induced during embryonic development or on postnatal day 21 were 6,8±0,6 and 7,2±0,6, respectively while adult and primiparous animals developed less than 2 …
p-IGF-IR Antibody 2B9
This Anti-IGF-IR Ab-1 Mouse mAb αIR3 is validated for use in IF, IP, Neutralization Studies, Paraffin Sections, Immunoblotting for the detection of IGF-IR Ab-1, – Find MSDS or SDS, a COA, data sheets and more information,
IGF-IR Antibody 3B7
La signalisation du facteur de croissance analogue à l’insuline I IGF-I induit un programme de transition épithéliale vers mésenchymateuse EMT et contribue aux métastases et à la résistance aux médicaments dans plusieurs sous-types de tumeurs Dans le
Both IGF-IR and IGF-IIR were overexpressed in GBMs compared with normal brain P<10−4 and P=0002 respectively Moreover, with regard to standard …
Insulin receptor IR and insulin-like growth factor
Insulin-like growth factor 1 receptor
Overview
Signalisation IGF-IR Dans La Transition épithéliale Vers
L’anticorps p-IGF-IR 2B9 est un anticorps monoclonal Anti-IGF-1 Receptor phospho-spécifique recommandé pour WB et IP, Cité dans 4 publications
Anti-IGF-IR Ab-1 Mouse mAb αIR3
Anti-IGF-IR Antibody, β-subunit, clone 1-2: Background Information: IGF-I and -II signal through the IGF-I Receptor, which is homologous to the Insulin Receptor, The high-affinity IGF-II Receptor does not play a direct role in signaling, but regulates the concentration of free IGF-II, The IGFs are involved in skeletal growth, and are essential
IGF-IR Promotes Prostate Cancer Growth by Stabilizing α5β1
Therapeutic strategy for IGF-1R and IR inhibition mainly encompasses three main approaches namely receptor blockade with monoclonal antibodies tyrosine kinase inhibition ATP antagonist and non-ATP antagonist and ligand neutralization via monoclonal antibodies targeted to ligand or recombinant IGF-binding proteins Other drug-discovery approaches are employed to target IGF-1R, and IR
Le récepteur de l’IGF1 et les hybrides IR/IGF1R Groupe
L’anticorps IGF-IR 3B7 est un anticorps monoclonal Anti-IGF-1 Receptor qui détecte IGF-I de m, r et h par IP et FCM, Cité dans 34 publications
IGF-IR δ1-958 Protein, active, 20 µg
Results: Both IGF-IR and IGF-IIR were overexpressed in GBMs compared with normal brain P<10-4 and P=0002 respectively Moreover with regard to standard clinical factors IGF-IR positivity was identified as an independent prognostic factor associated with shorter survival P=0016 and was associated with a less favourable response to temozolomide, Conclusions: This study suggests that
igf ir
IGF-IR: a new prognostic biomarker for human glioblastoma
igf-ir
IGF-IR δ1-958 Protein, active, 20 µg Active, N-terminal His6-tagged, recombinant human IGF-IR residues 959-end, for use in Kinase Assays, – Find MSDS or …
IGF-IR: a new prognostic biomarker for human glioblastoma
L’IR et l’IGF1R partagent plusieurs substrats IRS1 Shc … et plusieurs voies de signalisation voie de MAP kinases voie PI3-kinase/PKB… L’IGF1R est généralement considéré comme un récepteur contrôlant la croissance cellulaire alors que l’IR est plutôt considéré comme un récepteur contrôlant le métabolisme énergétique Cependant, les effets biologiques induits par ces
Traductions en contexte de “igf-ir” en anglais-français avec Reverso Context : nanobodies and polypeptides against egfr and igf-ir